Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913057 | 0.94 | NR5A1 (0.34) | TSHRLTA4HNR5A1RAB9ANPC1 | |
| SCHEMBL9574272 | 0.93 | NR5A1 (0.37) | TSHRLTA4HNR5A1RAB9ANPC1 | |
| SCHEMBL9574530 | 0.93 | NR5A1 (0.37) | TSHRLTA4HNR5A1RAB9ANPC1 | |
| SCHEMBL9574284 | 0.93 | NR5A1 (0.37) | TSHRLTA4HNR5A1RAB9ANPC1 | |
| SCHEMBL17870842 | 0.92 | RARB (0.36) | TSHRRAB9ACYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL3861302 | 0.78 | HRH3 (0.40) | LTA4HALDH1A1HRH3 | |
| SCHEMBL8852571 | 0.77 | ELANE (0.40) | TSHRCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8271040 | 0.74 | NFE2L2 (0.33) | — | |
| SCHEMBL5108597 | 0.74 | LTA4H (0.41) | LTA4HCHRM2CHRM1KCNH2 | |
| SCHEMBL5253017 | 0.72 | PSMB1 (0.45) | LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912549-A4 | COMPOUNDS AND METHODS FOR PROVIDING PHARMACOLOGICALLY ACTIVE PREPARATIONS AND USES THEREOF | UNIV TEXAS (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-0912549-A1 | COMPOUNDS AND METHODS FOR PROVIDING PHARMACOLOGICALLY ACTIVE PREPARATIONS AND USES THEREOF | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997048694-A1 | COMPOUNDS AND METHODS FOR PROVIDING PHARMACOLOGICALLY ACTIVE PREPARATIONS AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-12-24 | — | — | WO | disclosed |
| EP-0304018-A2 | Process for the preparation of aryl-(1-phthalimido)alkyl ketones | Degussa Aktiengesellschaft (DE) | 1989-02-22 | — | — | EP | disclosed |