Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 3/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596925 | 0.78 | SOAT1 (0.49) | BACE1CDC25AALDH1A1MEN1GAA | |
| SCHEMBL7597937 | 0.77 | SOAT1 (0.50) | BACE1CDC25AALDH1A1MEN1GAA | |
| SCHEMBL7601133 | 0.77 | SOAT1 (0.50) | BACE1CDC25AALDH1A1MEN1GAA | |
| SCHEMBL7600067 | 0.76 | BACE1 (0.56) | BACE1CDC25ACDC25BALDH1A1MAOA | |
| SCHEMBL7596986 | 0.73 | BACE1 (0.53) | BACE1CDC25ACDC25BALDH1A1MAOA | |
| SCHEMBL28808062 | 0.71 | PKM (0.48) | CDC25ACDC25BALDH1A1MAOAMAOB | |
| SCHEMBL7602692 | 0.69 | BACE1 (0.45) | BACE1CDC25ACDC25BALDH1A1MAOA | |
| SCHEMBL7599738 | 0.69 | BACE1 (0.51) | BACE1CDC25ACDC25BALDH1A1MAOA | |
| SCHEMBL6555840 | 0.68 | BACE1 (0.75) | BACE1CDC25ACDC25BALDH1A1MAOA | |
| SCHEMBL28463389 | 0.68 | CDC25B (0.53) | CDC25ACDC25BALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | disclosed |
| EP-0861830-A1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | L'OREAL (FR) | 1998-09-02 | — | — | EP | disclosed |