Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM6A | O15550 | 1/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | KDM4B | O94953 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.49 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16861478 | 0.87 | KMT2A (0.51) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL15328529 | 0.87 | KDM4E (0.49) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL6962756 | 0.85 | KDM4E (0.68) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL26654648 | 0.83 | P2RX7 (0.50) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL7982959 | 0.80 | MEN1 (0.50) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL17113034 | 0.80 | KDM4E (0.71) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL6970751 | 0.76 | KDM4E (0.47) | KDM4EL3MBTL1KMT2ATP53MEN1 | |
| SCHEMBL4699764 | 0.76 | PDE4A (0.62) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL196848 | 0.76 | KMT2A (0.68) | KDM4EL3MBTL1KMT2ATP53MEN1 | |
| Ethane SCHEMBL27460273 | 0.75 | PDE4A (0.61) | KDM4EL3MBTL1KDM4AEGLN1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479436-B1 | SUCH AS 2-(8-BROMOQUINOLIN-5-YL)CARBONYL-1,3-CYCLOHEXANEDIONE | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |