Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962761 | 0.86 | KDM4E (0.46) | KDM4ETDP1CYP3A4ALOX12TP53 | |
| SCHEMBL8303733 | 0.82 | KDM4E (0.50) | KDM4ETDP1CYP3A4ALOX12TP53 | |
| SCHEMBL27750929 | 0.81 | KDM4E (0.44) | KDM4ETDP1CYP3A4ALOX12GAA | |
| SCHEMBL7603841 | 0.76 | KDM4E (0.51) | KDM4ETDP1TP53HTTSMN1; SMN2 | |
| SCHEMBL12566073 | 0.76 | NSD2 (0.54) | KDM4ETDP1TP53HTTSMN1; SMN2 | |
| SCHEMBL2828660 | 0.74 | S1PR4 (0.43) | KDM4ETDP1CYP3A4ALOX12GAA | |
| SCHEMBL27516186 | 0.73 | KDM4E (0.50) | KDM4ETDP1CYP3A4ALOX12HTT | |
| SCHEMBL10773502 | 0.72 | TSHR (0.50) | TDP1GAAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL196848 | 0.72 | KMT2A (0.68) | KDM4ETDP1CYP3A4ALOX12TP53 | |
| SCHEMBL2593534 | 0.72 | MEN1 (0.43) | KDM4ETDP1CYP3A4ALOX12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931070-B1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |