SCHEMBL196848

SCHEMBL196848

Brc1ccc(Br)c2ncccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.68
MEN1 O00255 3/20 0.68
MAPT P10636 3/20 0.68
APAF1 O14727 1/20 0.68
TDP2 O95551 1/20 0.68
ALDH1A1 P00352 1/20 0.68
CASP3 P42574 1/20 0.68
SENP8 Q96LD8 1/20 0.68
SENP7 Q9BQF6 1/20 0.68
SENP6 Q9GZR1 1/20 0.68
KDM4E B2RXH2 6/20 0.57
HTT P42858 4/20 0.57
HSP90AA1 P07900 4/20 0.57
TP53 P04637 4/20 0.57
TDP1 Q9NUW8 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
USP2 O75604 1/20 0.57
SLC40A1 Q9NP59 2/20 0.50
L3MBTL1 Q9Y468 4/20 0.48
NPC1 O15118 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777336 0.83 KMT2A (0.59) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL29980123 0.83 KDM4E (0.61) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL29779851 0.83 KDM4E (0.61) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL10159159 0.83 KDM4E (0.61) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL2170981 0.83 KMT2A (0.59) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL18980424 0.83 KMT2A (0.59) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL12566070 0.83 KDM4E (0.55) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL31071884 0.83 KMT2A (0.96) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL16798532 0.83 KMT2A (0.59) KMT2AMEN1MAPTAPAF1TDP2
SCHEMBL29777332 0.83 KMT2A (0.59) KMT2AMEN1MAPTAPAF1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041905-B Fluorescent and phosphorescent dual luminescent material with switching effect and preparation method thereof 华中科技大学 2020-05-19 CN claimed
CN-103923102-A Synthesis method of compound 5, 8-di (3, 4-ethylenedioxy-thienyl) -quinoline NANJING UNIVERSITY OF TECHNOLOGY 2014-07-16 CN claimed
US-12606533-B2 3-phenylpropylamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-11-20 US disclosed
EP-4577016-A1 OPTICAL OUTCOUPLING MATERIAL, ORGANIC LIGHT EMITTING DEVICE, DISPLAY DEVICE, PROCESS FOR PREPARING THE ORGANIC LIGHT EMITTING DEVICE AND COMPOUND Novaled GmbH (DE) 2025-06-25 EP disclosed
CN-107814795-B Compounds as URAT1 inhibitors 江苏艾立康药业股份有限公司 2020-12-18 CN disclosed
CN-112062758-A Selenophenol quinoline derivative and preparation method and application thereof 广州新民培林医药科技有限公司 2020-12-11 CN disclosed
CN-107619410-B Compound and organic electronic element comprising same 株式会社LG化学 2020-11-27 CN disclosed
US-10680183-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
CN-110041905-B Fluorescent and phosphorescent dual luminescent material with switching effect and preparation method thereof 华中科技大学 2020-05-19 CN disclosed
US-20190173021-A1 NITROGEN HETEROCYCLE-FUSED BENZENE-BENZIMIDAZOLE ORGANIC COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2019-06-06 US disclosed
US-20090326188-A1 Method for producing polyarylene SUMITOMO CHEMICAL COMPANY, LIMITED 2009-12-31 US disclosed
EP-2065420-A1 METHOD FOR PRODUCING POLYARYLENE Sumitomo Chemical Company, Limited (JP) 2009-06-03 EP disclosed
EP-1006135-B1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN IND LTD (JP) 2003-02-12 EP disclosed
EP-0787719-B1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN IND LTD (JP) 2001-08-16 EP disclosed
EP-1006135-A1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN INDUSTRIES, LIMITED (JP) 2000-06-07 EP disclosed
US-5736274-A ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING DAIKIN INDUSTRIES, LTD. (JP) 1998-04-07 US disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed
US-5367038-A Polyisoquinolinediyls and uses thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1994-11-22 US disclosed
US-5244992-A Poly(iso)quinolinediyls and preparation and use thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1993-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE SF1, SF3A1, SFXN1 KMT2A 1381/4885MEN1 2763/4885MAPT 2719/4885
US-10680183-B2 Organic electroluminescent materials and devices PNMT, CYCS, NES KMT2A 2500/4885MEN1 2648/4885MAPT 198/4885
US-12606533-B2 3-phenylpropylamine derivative SF3A1, SF1, HTR1D KMT2A 1072/4885MEN1 3086/4885MAPT 4210/4885
US-20190173021-A1 NITROGEN HETEROCYCLE-FUSED BENZENE-BENZIMIDAZOLE ORGANIC COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS OCIAD1, OCIAD2, CTNND1 KMT2A 4247/4885MEN1 4885/4885MAPT 773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.