Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208446 | 0.81 | TP53 (0.42) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL7642852 | 0.80 | TDP1 (0.52) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL30250666 | 0.79 | TP53 (0.61) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL1758394 | 0.79 | TP53 (0.61) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL31547677 | 0.76 | TDP1 (0.52) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL3043421 | 0.76 | TDP1 (0.52) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL17827072 | 0.75 | TP53 (0.56) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL5088743 | 0.74 | TP53 (0.56) | TP53TDP1TRPA1NPC1RAB9A | |
| SCHEMBL6068072 | 0.74 | TP53 (0.54) | TP53TDP1TRPA1LCKESR1 | |
| SCHEMBL2934180 | 0.73 | ALDH1A1 (0.46) | TP53TDP1TRPA1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704437-B1 | Red-shifted tris-aryl-s-triazines and compositions stabilized therewith | CIBA SC HOLDING AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| US-5849821-A | Tris-aryl-s-triazines substituted with biphenylyl groups | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| US-5726309-A | ULTRAVIOLET RADIATION ABSORBERS; THERMAL STABILIZERS FOR POLYMER SUBSTRATES, ESPECIALLY AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0826675-A1 | Tris-aryl s-triazines substituted with biphenylyl groups | Ciba SC Holding AG (CH) | 1998-03-04 | — | — | EP | disclosed |
| US-5684070-A | FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5681955-A | PHOTOSTABILITY OF POLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| US-5675004-A | POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS | CIBA-GEIGY CORPORATION (US) | 1997-10-07 | — | — | US | disclosed |
| US-5648488-A | Compositions stabilized with red-shifted tris-aryl-s-triazines | CIBA-GEIGY CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |
| US-5637706-A | ACTINIC RADIATION STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5556973-A | Red-shifted tris-aryl-s-triazines and compositions stabilized therewith | CIBA-GEIGY CORPORATION (US) | 1996-09-17 | — | — | US | disclosed |
| US-5543518-A | ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES | CIBA-GEIGY CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0704437-A2 | Red-shifted tris-aryl-s-triazines and compositions stabilized therewith | CIBA-GEIGY AG (CH) | 1996-04-03 | — | — | EP | disclosed |