Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459798 | 0.80 | AHR (0.50) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 | |
| Water SCHEMBL9697542 | 0.79 | CYP3A4 (0.48) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 | |
| SCHEMBL10535935 | 0.78 | HPGD (0.46) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 | |
| SCHEMBL2230314 | 0.76 | CYP3A4 (0.67) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 | |
| SCHEMBL30034845 | 0.76 | CYP3A4 (0.67) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 | |
| SCHEMBL7081176 | 0.75 | AHR (0.45) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 | |
| SCHEMBL29807938 | 0.75 | ALDH1A1 (0.62) | HPGDHSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL1022489 | 0.75 | ALDH1A1 (0.62) | HPGDHSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL7106910 | 0.74 | TSHR (0.62) | HPGDHSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL30444732 | 0.74 | AHR (0.48) | HPGDHSD17B10TSHRCYP3A4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115117-A1 | ERbeta-mediated gene expression | MASSACHUSETTS, UNIVERSITY OF | 2002-08-22 | — | — | US | disclosed |