Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554208 | 0.88 | HTR2A (0.52) | HTR2AMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL7561636 | 0.84 | MAPT (0.52) | HTR2AMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7608786 | 0.83 | ENO1 (0.44) | MAPTALDH1A1L3MBTL1GAACXCR4 | |
| SCHEMBL7972343 | 0.79 | ENO1 (0.40) | MAPTALDH1A1L3MBTL1POLBCXCR4 | |
| SCHEMBL3037119 | 0.78 | HTR2A (0.68) | HTR2AMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23616423 | 0.78 | HTR2A (0.42) | HTR2AMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7556391 | 0.76 | ENO1 (0.42) | MAPTALDH1A1MAPK1GAAPOLB | |
| SCHEMBL25189373 | 0.76 | HTR2A (0.65) | HTR2AMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30880314 | 0.76 | HTR2A (0.56) | HTR2AMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28709983 | 0.76 | HTR2A (0.57) | HTR2AMAPTALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |