Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7951764 | 0.98 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL7608951 | 0.88 | ALDH1A1 (0.56) | TDP1USP2HTR2AKDM4EALDH1A1 | |
| SCHEMBL20305813 | 0.88 | MEN1 (0.62) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL7607619 | 0.86 | ALDH1A1 (0.57) | TDP1USP2HTR2AKDM4EALDH1A1 | |
| SCHEMBL8059627 | 0.85 | HRH1 (0.52) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL6558636 | 0.85 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL29175115 | 0.84 | HRH1 (0.53) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL28377294 | 0.84 | HRH1 (0.61) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL13460805 | 0.81 | SMN1; SMN2 (0.58) | HRH1TDP1USP2HRH2HTR2A | |
| SCHEMBL20305526 | 0.81 | MEN1 (0.54) | HRH1TDP1USP2SLC6A2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | claimed |
| EP-0927173-A1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB, S.A. (BE) | 1999-07-07 | — | — | EP | claimed |
| WO-1997037982-A1 | NOVEL SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB S.A. (BE) | 1997-10-16 | — | — | WO | claimed |
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | disclosed |
| CN-1072661-C | Novel substituted [2-(1-piperazinyl) ethoxy] methyl | UCB SA (BE) | 2001-10-10 | — | — | CN | disclosed |
| US-6255487-B1 | PREPARING 2-(2-(4-((4-CHLOROPHENYL)PHENYLMETHYL)-1-PIPER-AZINYL)ETHOXY)ACETIC ACID VIA REACTING SUBSTITUTED (2-((1-PIPERAZINYL)ETHOXY)METHYL COMPOUND WITH A DIPHENYLMETHYL HALIDE, THEN HYDROLYZING IN ALCOHOLIC MEDIUM WITH ACID/BASE | UCB, S.A. (BE) | 2001-07-03 | — | — | US | disclosed |
| US-6140501-A | CHEMICAL INTERMEDIATES | UCB, S.A. (BE) | 2000-10-31 | — | — | US | disclosed |
| CN-1215395-A | Novel substituted [2-(1-piperazinyl) ethoxy] methyl | UCB SA (BE) | 1999-04-28 | — | — | CN | disclosed |