Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29175115 | 0.99 | HRH1 (0.53) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL7604178 | 0.85 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL10930677 | 0.85 | HRH1 (0.53) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL8804632 | 0.84 | SMN1; SMN2 (0.51) | HRH1TDP1USP2HRH2HTR2A | |
| SCHEMBL6558636 | 0.84 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL7951764 | 0.84 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL28377294 | 0.83 | HRH1 (0.61) | HRH1TDP1USP2SLC6A2HRH2 | |
| SCHEMBL219876 | 0.83 | HRH1 (0.59) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL5686168 | 0.82 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 | |
| Hydrochloric Acid SCHEMBL219199 | 0.82 | HRH1 (0.60) | HRH1TDP1USP2SLC6A2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121643-B1 | NEW PROCESS FOR THE PREPARATION OF LEVOCETIRIZINE AND INTERMEDIATES THEREOF | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2013-10-23 | — | — | EP | disclosed |
| US-6046332-A | Methods for the manufacture of cetirizine | TAO YONG (CA) | 2000-04-04 | — | — | US | disclosed |
| US-6046332-A | Methods for the manufacture of cetirizine | TAO YONG (CA) | 2000-04-04 | — | — | US | disclosed |
| WO-1998002425-A1 | METHODS FOR THE MANUFACTURE OF CETIRIZINE | APOTEX INC. (CA) | 1998-01-22 | — | — | WO | disclosed |
| WO-1998002425-A1 | METHODS FOR THE MANUFACTURE OF CETIRIZINE | APOTEX INC. (CA) | 1998-01-22 | — | — | WO | disclosed |