Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HRH2 | P25021 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.50 |
| ▸ | LSS | P48449 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28377294 | 0.99 | HRH1 (0.61) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| SCHEMBL7604178 | 0.85 | HRH1 (0.60) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| SCHEMBL8059627 | 0.84 | HRH1 (0.52) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7951764 | 0.83 | HRH1 (0.60) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| SCHEMBL219876 | 0.83 | HRH1 (0.59) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29175115 | 0.83 | HRH1 (0.53) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL219199 | 0.82 | HRH1 (0.60) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5686168 | 0.82 | HRH1 (0.60) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| SCHEMBL13073679 | 0.82 | CACNA1G (0.53) | HRH1HTR2AHRH2SLC6A2SLC6A4 | |
| SCHEMBL2058761 | 0.81 | HRH1 (0.57) | HRH1HTR2AHRH2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121643-B1 | NEW PROCESS FOR THE PREPARATION OF LEVOCETIRIZINE AND INTERMEDIATES THEREOF | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2013-10-23 | — | — | EP | disclosed |
| US-20040186112-A1 | Polymorphic forms of dihydrochloride salts of cetirizine and processes for preparation thereof | DR. REDDY'S LABORATORIES LIMITED | 2004-09-23 | — | — | US | disclosed |
| WO-2004050647-A2 | POLYMORPHIC FORMS OF DIHYDROCHLORIDE SALTS OF CETIRIZINE AND PROCESSES FOR PREPARATION THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2004-06-17 | — | — | WO | disclosed |
| US-6046332-A | Methods for the manufacture of cetirizine | TAO YONG (CA) | 2000-04-04 | — | — | US | disclosed |
| US-6046332-A | Methods for the manufacture of cetirizine | TAO YONG (CA) | 2000-04-04 | — | — | US | disclosed |
| WO-1998002425-A1 | METHODS FOR THE MANUFACTURE OF CETIRIZINE | APOTEX INC. (CA) | 1998-01-22 | — | — | WO | disclosed |
| WO-1998002425-A1 | METHODS FOR THE MANUFACTURE OF CETIRIZINE | APOTEX INC. (CA) | 1998-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186112-A1 | Polymorphic forms of dihydrochloride salts of cetirizine and processes for preparation thereof | HRH1, HRH4, HRH2 | HRH1 1/4885HTR2A 153/4885HRH2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.