SCHEMBL7604279

SCHEMBL7604279

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(I)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 2/20 0.50
TAS1R3 Q7RTX0 1/20 0.50
TAS1R1 Q7RTX1 1/20 0.50
TAS1R2 Q8TE23 1/20 0.50
JAK2 O60674 1/20 0.50
CYP3A4 P08684 1/20 0.50
JAK1 P23458 1/20 0.50
KMT2A Q03164 3/20 0.49
PPIA P62937 1/20 0.47
TDP1 Q9NUW8 1/20 0.45
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 2/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichlorbenzuron SCHEMBL3663126 0.87 CNR1 (0.54) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL11244841 0.86 MAOA (0.51) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL7605864 0.85 KMT2A (0.61) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL7603457 0.84 KMT2A (0.59) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL9352624 0.84 NPC1 (0.50) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL8840291 0.84 PPIA (0.47) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL7600272 0.84 GAA (0.55) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL7604719 0.84 EPHX1 (0.46) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL30499674 0.84 EPHX1 (0.46) TYK2TAS1R3TAS1R1TAS1R2JAK2
SCHEMBL7606210 0.83 SMO (0.57) TYK2TAS1R3TAS1R1TAS1R2JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-4833151-A INTERFERES WITH METAMORPHOSES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-05-23 US disclosed
US-4607044-A Insecticidal use of ureas and thioureas DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1986-08-19 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4110469-A Insecticidal N-(2,6-dichlorobenzoyl)-N'-(4-cyanophenyl) urea U.S. PHILIPS CORPORATION (US) 1978-08-29 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 TYK2 1902/4885TAS1R3 2575/4885TAS1R1 2597/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 TYK2 1902/4885TAS1R3 2575/4885TAS1R1 2597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.