SCHEMBL7605864

SCHEMBL7605864

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.61
MEN1 O00255 6/20 0.61
RAB9A P51151 5/20 0.61
NPC1 O15118 5/20 0.61
MAPT P10636 6/20 0.57
LMNA P02545 4/20 0.57
JAK2 O60674 2/20 0.54
TYK2 P29597 2/20 0.54
CYP3A4 P08684 1/20 0.54
JAK1 P23458 1/20 0.54
PPIA P62937 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
TP53 P04637 1/20 0.53
EPHX1 P07099 1/20 0.53
TSHR P16473 1/20 0.53
EPHX2 P34913 1/20 0.53
CDK9 P50750 1/20 0.53
CLK4 Q9HAZ1 1/20 0.53
HTT P42858 2/20 0.53
POLB P06746 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL10392049 0.95 KMT2A (0.56) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL7606210 0.91 SMO (0.57) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL11078178 0.89 JAK2 (0.59) KMT2AMEN1RAB9ANPC1MAPT
Dichlorbenzuron SCHEMBL3663126 0.88 CNR1 (0.54) KMT2AMEN1RAB9ANPC1LMNA
SCHEMBL9348931 0.88 RAB9A (0.55) KMT2AMEN1RAB9ANPC1JAK2
SCHEMBL11244841 0.87 MAOA (0.51) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL7603162 0.87 ITGB1 (0.48) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL9348852 0.87 KMT2A (0.46) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL4154853 0.85 TYK2 (0.71) KMT2AMEN1MAPTLMNAJAK2
SCHEMBL30499670 0.85 KMT2A (0.67) KMT2AMEN1RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-4323579-A Insecticidal N-(p-aminophenyl)-N'-benzoylureas CIBA-GEIGY CORPORATION (US) 1982-04-06 US disclosed
US-4321276-A INSECTICIDE CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4310694-A CHEMICAL INTERMEDIATES OF BENZOYL UREAS CIBA-GEIGY CORPORATION (US) 1982-01-12 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885RAB9A 1813/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885RAB9A 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.