SCHEMBL7604431

SCHEMBL7604431

O=C1C=CC(=O)N1OC(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15712138 0.68 PARL (0.33)
SCHEMBL10666060 0.67 MGLL (0.42) MGLLGSK3AGSK3BFAAH
SCHEMBL7139394 0.67 MGLL (0.42) MGLLGSK3AGSK3BFAAH
SCHEMBL2383424 0.67 MGLL (0.30) MGLL
SCHEMBL14789774 0.67 MGLL (0.39) MGLLGSK3AGSK3BFAAH
SCHEMBL2111704 0.65 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL3482921 0.63 MGLL (0.38) MGLLGSK3AGSK3BFAAH
SCHEMBL865686 0.59 ALDH1A1 (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL21419589 0.59 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL21840474 0.59 MGLL (0.35) MGLLGSK3AGSK3BFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0726252-B1 Process for the preparation of N-substituted cyclic imides BAYER AG (DE) 2002-04-17 EP disclosed
US-5773630-A REACTION OF ANHYDRIDE WITH PRIMARY AMINE TO FORM CYCLIC IMIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
EP-0726252-A1 Process for the preparation of N-substituted cyclic imides BAYER AG (DE) 1996-08-14 EP disclosed