SCHEMBL7604461

SCHEMBL7604461

CCCCCCOc1cc(O)c(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRA P10827 3/20 0.43
THRB P10828 3/20 0.43
SOAT1 P35610 1/20 0.43
PTPN11 Q06124 2/20 0.42
CNR2 P34972 1/20 0.42
TLR8 Q9NR97 2/20 0.41
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
SMPD1 P17405 1/20 0.39
PTPN1 P18031 2/20 0.39
LTB4R Q15722 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28789426 0.87 ESR1 (0.44) THRATHRBSOAT1PTPN11CNR2
SCHEMBL8848177 0.85 LTB4R (0.44) THRATHRBSOAT1PTPN11CNR2
SCHEMBL8848364 0.85 LTB4R (0.44) THRATHRBSOAT1PTPN11CNR2
SCHEMBL28863430 0.83 THRA (0.41) THRATHRBSOAT1PTPN11CNR2
SCHEMBL7603039 0.81 THRA (0.41) THRATHRBSOAT1PTPN11CNR2
SCHEMBL5672495 0.81 SOAT1 (0.44) THRATHRBSOAT1PTPN11CNR2
SCHEMBL3791722 0.81 THRA (0.49) THRATHRBSOAT1PTPN11CNR2
SCHEMBL676845 0.80 SMPD1 (0.51) THRATHRBSOAT1PTPN11CNR2
SCHEMBL8376351 0.79 PTPN11 (0.49) THRATHRBPTPN11CNR2PTPN1
SCHEMBL1467411 0.79 PTPN11 (0.54) PTPN11CNR2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-B1 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA SC HOLDING AG (CH) 2002-09-25 EP claimed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
EP-0704437-B1 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA SC HOLDING AG (CH) 2002-09-25 EP disclosed
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed
US-5648488-A Compositions stabilized with red-shifted tris-aryl-s-triazines CIBA-GEIGY CORPORATION (US) 1997-07-15 US disclosed
US-5637706-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5556973-A Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1996-09-17 US disclosed
US-5543518-A ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES CIBA-GEIGY CORPORATION (US) 1996-08-06 US disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed