SCHEMBL676845

SCHEMBL676845

CCCCCCOc1cc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)ccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 1/20 0.51
PTPN11 Q06124 4/20 0.48
BCHE P06276 1/20 0.48
ACHE P22303 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
TRPV1 Q8NER1 1/20 0.46
CNR2 P34972 1/20 0.45
TLR8 Q9NR97 2/20 0.44
SOAT1 P35610 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
NPC1 O15118 1/20 0.43
GLA P06280 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16415394 0.95 BCHE (0.53) SMPD1PTPN11BCHEACHEESR1
SCHEMBL8424888 0.83 SMPD1 (0.52) SMPD1PTPN11ESR1ESR2TRPV1
SCHEMBL29111485 0.82 ESR1 (0.51) SMPD1PTPN11BCHEACHEESR1
SCHEMBL28471470 0.81 BCHE (0.40) SMPD1BCHEACHEESR1ESR2
SCHEMBL28789426 0.81 ESR1 (0.44) SMPD1PTPN11BCHEACHEESR1
SCHEMBL5270285 0.81 SMPD1 (0.46) SMPD1PTPN11ESR1ESR2TRPV1
SCHEMBL15153781 0.81 PTPN11 (0.44) PTPN11BCHEACHECNR2TLR8
SCHEMBL17599779 0.80 GAA (0.41) SMPD1PTPN11BCHEACHEESR1
SCHEMBL7604461 0.80 THRA (0.43) SMPD1PTPN11BCHEACHECNR2
SCHEMBL7620596 0.80 PTPN11 (0.49) SMPD1PTPN11TLR8THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368629-A Stabilizer composition and method for protecting organic materials from UV light and thermal degradation using the same 塞特工业公司 2022-11-22 CN claimed
US-20210403690-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING POLYMERIC ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2021-12-30 US claimed
US-11091615-B2 Stabilizer compositions and methods for using same for protecting organic materials from UV light and thermal degradation CYTEC INDUSTRIES INC. (US) 2021-08-17 US claimed
US-10975278-B2 Granular stabilizer compositions for use in polymer resins and methods of making same CYTEC INDUSTRIES INC. (US) 2021-04-13 US claimed
CN-112055728-A Particulate stabilizer composition for polymer resins and process for producing the same 塞特工业公司 2020-12-08 CN claimed
US-20190264084-A1 GRANULAR STABILIZER COMPOSITIONS FOR USE IN POLYMER RESINS AND METHODS OF MAKING SAME CYTEC INDUSTRIES INC. (US) 2019-08-29 US claimed
EP-3221393-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION Cytec Industries Inc. (US) 2017-09-27 EP claimed
US-20160145427-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. 2016-05-26 US claimed
WO-2016081823-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2016-05-26 WO claimed
US-20050005285-A1 Method of protecting light sensitive optical article GENERAL ELECTRIC COMPANY 2005-01-06 US claimed
US-11952460-B2 Polycarbonate resin, method for producing the same, and optical lens MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-09 US disclosed
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-07 US disclosed
WO-2023208837-A1 OLIGOMERIC BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-11-02 WO disclosed
US-11760712-B2 Triarylmethane compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-19 US disclosed
CN-112055728-B Granular stabilizer composition for polymer resin and method for producing the same 塞特工业公司 2023-05-05 CN disclosed
US-20020103279-A1 Polyester overlamination film with enhanced UV stabilization properties TORAY PLASTICS (AMERICA), INC., A RHODE ISLAND CORPORATION 2002-08-01 US disclosed
EP-1213614-A1 Polyester overlamination film with enhanced uv stabilization properties Toray Plastics (America), Inc. (US) 2002-06-12 EP disclosed
US-20020028862-A1 Light stable articles 3M INNOVATIVE PROPERTIES COMPANY 2002-03-07 US disclosed
EP-0915756-A1 MULTILAYERED CRYSTALLIZABLE THERMOPLASTIC PLATE, PROCESS FOR ITS PRODUCTION AND USE THEREOF Hostaglas Ltd. (IE) 1999-05-19 EP disclosed
WO-1998005496-A1 MULTILAYERED CRYSTALLIZABLE THERMOPLASTIC PLATE, PROCESS FOR ITS PRODUCTION AND USE THEREOF AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS CBR3, HAX1, HRH3 SMPD1 4652/4885PTPN11 2619/4885BCHE 3966/4885
US-11760712-B2 Triarylmethane compounds CBR3, HAX1, HRH3 SMPD1 4652/4885PTPN11 2619/4885BCHE 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.