SCHEMBL760452

SCHEMBL760452

FC(F)(F)c1[c]cc[c]c1C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585620 0.70
SCHEMBL81364 0.70
SCHEMBL5314612 0.70 CYP3A4 (0.41)
SCHEMBL19133532 0.68
SCHEMBL225527 0.68 TSHR (0.33)
SCHEMBL3428550 0.68 ALOX15 (0.33)
SCHEMBL1966362 0.68 NOTUM (0.33)
SCHEMBL456308 0.68
SCHEMBL15063792 0.68 TRPA1 (0.30)
SCHEMBL20607524 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9244345-B1 Non-ionic photo-acid generating polymers for resist applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-01-26 US claimed
US-7597945-B2 Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties CHISSO CORPORATION (JP) 2009-10-06 US claimed
US-7588806-B2 Homeotropically aligned liquid crystal film and process for producing the same CHISSO CORPORATION (JP) 2009-09-15 US claimed
US-7527746-B2 Liquid crystal polyfunctional acrylate derivative and polymer thereof CHISSO CORPORATION (JP) 2009-05-05 US claimed
US-7425354-B2 Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element CHISSO CORPORATION (JP) 2008-09-16 US claimed
US-20070128379-A1 Homeotropically aligned liquid crystal film and process for producing the same JNC PETROCHEMICAL CORPORATION (JP) 2007-06-07 US claimed
US-20060172090-A1 Liquid crystal polyfunctional acrylate derivative and polymer thereof JNC PETROCHEMICAL CORPORATION (JP) 2006-08-03 US claimed
US-7070838-B2 Liquid crystalline compound, liquid crystal composition and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2006-07-04 US claimed
US-20060134350-A1 Polymerizable liquid crystal composition containing fluorine-substituted (meth) acrylate derivatives JNC PETROCHEMICAL CORPORATION (JP) 2006-06-22 US claimed
US-20050213009-A1 Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element JNC PETROCHEMICAL CORPORATION (JP) 2005-09-29 US claimed
EP-1245660-B1 Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices CHISSO CORP (JP) 2005-02-23 EP claimed
US-6844032-B2 Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 2005-01-18 US claimed
US-20050007541-A1 Liquid crystalline compound, liquid crystal composition and their polymers JNC PETROCHEMICAL CORPORATION (JP) 2005-01-13 US claimed
US-20030077405-A1 Liquid crystal compounds having bis(trifluoromethyl) phenyl rings, liquid crystal compositions and liquid crystal display devices JNC PETROCHEMICAL CORPORATION (JP) 2003-04-24 US claimed
EP-1245660-A2 Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 2002-10-02 EP claimed
US-10633589-B2 Liquid crystal medium, optical device and liquid crystal compound JNC CORPORATION (JP) 2020-04-28 US disclosed
EP-2774968-B1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2019-11-20 EP disclosed
JP-2002371026-A LIQUID CRYSTAL COMPOUND HAVING BIS(TRIFLUOROMETHYL) PHENYL RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORP 2002-12-26 JP disclosed
EP-1245660-A2 Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 2002-10-02 EP disclosed
EP-1245660-A2 Liquid crystal compounds having bis(trifluoromethyl)phenyl rings, liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 2002-10-02 EP disclosed