Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450127 | 0.86 | MEN1 (0.80) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL7449268 | 0.86 | MEN1 (0.68) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL27181012 | 0.83 | LMNA (0.62) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL7513013 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL4098366 | 0.80 | MEN1 (0.67) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL30926863 | 0.79 | MEN1 (0.59) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL27181090 | 0.79 | MEN1 (0.59) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL7505369 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL6720181 | 0.78 | MEN1 (0.85) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL13870858 | 0.78 | MEN1 (0.82) | MEN1KMT2APOLBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |