Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | IDH1 | O75874 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181012 | 0.86 | LMNA (0.62) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL7450127 | 0.83 | MEN1 (0.80) | MEN1KMT2APOLBMAPTHDAC2 | |
| SCHEMBL7449268 | 0.83 | MEN1 (0.68) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL30926863 | 0.82 | MEN1 (0.59) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL27181090 | 0.82 | MEN1 (0.59) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL7505369 | 0.82 | MEN1 (0.56) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL7604529 | 0.81 | MEN1 (0.66) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL15880109 | 0.80 | CASP3 (0.72) | MEN1KMT2AADORA3SLC6A3ALDH1A1 | |
| SCHEMBL4098366 | 0.79 | MEN1 (0.67) | MEN1KMT2AADORA3SLC6A3POLB | |
| SCHEMBL30926958 | 0.78 | MEN1 (0.88) | MEN1KMT2AADORA3SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |