Triphosphate

Triphosphate

SCHEMBL76046

Nc1cc[nH]c(=O)n1.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLG P54098 4/20 0.36
PNP P00491 1/20 0.34
POLB P06746 2/20 0.33
POLA1 P09884 1/20 0.33
DYRK1A Q13627 1/20 0.33
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytosine SCHEMBL10496378 0.98 POLG (0.38) POLGPNPPOLBPOLA1DYRK1A
Pyrophosphoric Acid SCHEMBL1144356 0.93 FDPS (0.34) POLGPOLBDYRK1AADORA2AADORA1
Cytosine SCHEMBL6908127 0.87 POLG (0.30) POLG
Cytosine SCHEMBL76045 0.86 DYRK1A (0.38) DYRK1AADORA2AADORA1TSHR
Cytosine SCHEMBL1629580 0.86 DYRK1A (0.38) DYRK1AADORA2AADORA1TSHR
Cytosine SCHEMBL1144358 0.86 DYRK1A (0.38) DYRK1AADORA2AADORA1TSHR
Cytosine SCHEMBL10496353 0.86 DYRK1A (0.38) DYRK1AADORA2AADORA1TSHR
Cytosine SCHEMBL26123983 0.84 DYRK1A (0.37) DYRK1AADORA2AADORA1TSHR
Cytosine SCHEMBL5356635 0.84 DYRK1A (0.37) DYRK1AADORA2AADORA1TSHR
Triphosphate SCHEMBL445185 0.83 POLG (0.33) POLGPNPPOLBPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2496 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596713-A1 DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF 4basebio UK Ltd (GB) 2025-08-06 EP claimed
CN-115219716-B Method for detecting carbendazim residue based on personal blood glucose meter 西南大学 2025-03-18 CN claimed
WO-2024250607-A1 CHEMICALLY MODIFIED CYTIDINE TRIPHOSPHATE AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院深圳先进技术研究院 2024-12-12 WO claimed
WO-2024250923-A1 CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF 中国科学院深圳先进技术研究院 2024-12-12 WO claimed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US claimed
CN-116113419-A Cyclic RNA compositions and methods 奥纳治疗公司 2023-05-12 CN claimed
CN-115807083-A Colorectal cancer gene mutation identification method, device and application 复旦大学附属中山医院 2023-03-17 CN claimed
EP-4146285-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2023-03-15 EP claimed
CN-115052635-A Circular RNA compositions and methods 奥纳治疗公司 2022-09-13 CN claimed
CN-114350581-A Escherichia coli for producing cytosine and construction method and application thereof 天津科技大学 2022-04-15 CN claimed
WO-2000036151-A1 A HETEROGENEOUS ASSAY FOR PYROPHOSPHATE DETECTION LI-COR, INC. (US) 2000-06-22 WO claimed
EP-0695366-A4 METHOD OF RANDOM AMPLIFICATION OF POLYMORPHIC DNA F B INVESTMENTS PTY LTD (AU) 1999-07-28 EP claimed
US-5902793-A ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 1999-05-11 US claimed
WO-1999006592-A9 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES NEW YORK MEDICAL COLLEGE (US) 1999-05-06 WO claimed
WO-1999006592-A1 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES NEW YORK MEDICAL COLLEGE (US) 1999-02-11 WO claimed
US-5759821-A Method of random amplification of polymorphic DNA F B INVESTMENTS PTY LTD (AU) 1998-06-02 US claimed
EP-0695366-A1 METHOD OF RANDOM AMPLIFICATION OF POLYMORPHIC DNA F B Investments Pty. Ltd. (AU) 1996-02-07 EP claimed
EP-0676476-A1 Isothermal strand displacement nucleic acid amplification GEN-PROBE INCORPORATED (US) 1995-10-11 EP claimed
WO-1995025180-A1 ISOTHERMAL STRAND DISPLACEMENT NUCLEIC ACID AMPLIFICATION GEN-PROBE INCORPORATED (US) 1995-09-21 WO claimed
WO-1994024307-A1 METHOD OF RANDOM AMPLIFICATION OF POLYMORPHIC DNA FORBIO PTY. LTD. (AU) 1994-10-27 WO claimed