Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30525916 | 1.00 | GABRA1 (0.31) | GABRA1GABRB2CA2 | |
| Hydrochloric Acid SCHEMBL5983907 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL3693058 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL30525926 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7030004 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6234366 | 0.79 | GABRA1 (0.31) | GABRA1GABRB2CA2 | |
| Hydrochloric Acid SCHEMBL8459011 | 0.79 | HSD11B1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL30203909 | 0.79 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2234634 | 0.79 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL16859782 | 0.78 | CYP3A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013217-A1 | CATALYST FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR ITS PREPARATION AND ITS USE | HANS-FRIEDRICH HERRMANN | 2002-01-31 | — | — | US | disclosed |