SCHEMBL7604923

SCHEMBL7604923

Cc1cccc([SiH](O)O)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 5/20 0.42
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
TSHR P16473 2/20 0.36
ACHE P22303 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 4/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
MEN1 O00255 1/20 0.32
AKR1B10 O60218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31310605 0.85 TRPA1 (0.48) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL2996960 0.81 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL23282548 0.81 TRPA1 (0.35) TRPA1ATMALDH1A1CYP1A2TSHR
SCHEMBL271788 0.79 TSHR (0.47) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL29776884 0.77 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL9363776 0.77 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL17721900 0.76 TRPA1 (0.40) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL2079047 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL8967432 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL9147737 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10995268-B2 Etching composition effective to selectively wet etch a silicon nitride film LTCAM CO., LTD. (KR) 2021-05-04 US disclosed
EP-0644231-B1 Crosslinking accelerator system for RTV polymers RHODIA CHIMIE SA (FR) 2002-01-02 EP disclosed
US-6124235-A COMPRISING CATALYST FOR CROSSLINKING THE POLYMERS BY POLYCONDENSATION, AT LEAST ONE SOLID INORGANIC COMPOUND CONTAINING AN AMOUNT Y OF WATER IN THE FORM OF WATER OF HYDRATION, FILLERS, DILUENTS, SOLVENTS RHONE-POULENC CHIMIE (FR) 2000-09-26 US disclosed
US-5681884-A SILICONES; ADHESIVES RHONE-POULENC CHIMIE (FR) 1997-10-28 US disclosed
EP-0644231-A1 Crosslinking accelerator system for RTV polymers RHONE-POULENC CHIMIE (FR) 1995-03-22 EP disclosed