SCHEMBL2996960

SCHEMBL2996960

Cc1cccc([SiH](O)[SiH3])c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 3/20 0.39
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ACHE P22303 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 3/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7604923 0.81 TRPA1 (0.48) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL15641904 0.81 TSHR (0.43) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL31310605 0.81 TRPA1 (0.48) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL29776884 0.73 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL9363776 0.73 TRPA1 (0.44) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL17721900 0.72 TRPA1 (0.40) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL8967363 0.71 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL8967432 0.71 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL9147737 0.71 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6
SCHEMBL2079047 0.71 TRPA1 (0.42) TRPA1ATMALDH1A1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110318680-A1 HYDROXYGALLIUM HYDROXYALUMINUM PHTHALOCYANINE SILANOL CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-7799497-B2 Silanol containing overcoated photoconductors XEROX CORPORATION (US) 2010-09-21 US claimed
US-7781132-B2 Silanol containing charge transport overcoated photoconductors XEROX CORPORATION (US) 2010-08-24 US claimed
US-7662527-B2 Silanol containing photoconductor XEROX CORPORATION (US) 2010-02-16 US claimed
US-7585602-B2 Imaging member having antistatic anticurl back coating containing polyhedral oligomeric silsequioxane silanol XEROX CORPORATION (US) 2009-09-08 US claimed
US-20080268356-A1 Silanol containing photoconductors XEROX CORPORATION. 2008-10-30 US claimed
US-20080107985-A1 Silanol containing overcoated photoconductors XEROX CORPORATION 2008-05-08 US claimed
US-20080107979-A1 Silanol containing charge transport overcoated photoconductors XEROX CORPORATION 2008-05-08 US claimed
US-20080057425-A1 Silanol containing perylene photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057423-A1 Titanyl phthalocyanine silanol terphenyl photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057421-A1 Silanol containing perylene photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057422-A1 Titanyl phthalocyanine silanol photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080032218-A1 Silanol containing photoconductor XEROX CORPORATION 2008-02-07 US claimed
US-20080020312-A1 Imaging member having antistatic anticurl back coating XEROX CORPORATION (US) 2008-01-24 US claimed
US-20080014517-A1 Silanol containing photoconductors XEROX CORPORATION. 2008-01-17 US claimed