Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310605 | 0.85 | TRPA1 (0.48) | TRPA1ATMCYP1A2LMNAMEN1 | |
| SCHEMBL18722127 | 0.78 | TRPA1 (0.37) | TRPA1ATMCYP1A2LMNAMEN1 | |
| SCHEMBL7604923 | 0.76 | TRPA1 (0.48) | TRPA1ATMCYP1A2LMNAMEN1 | |
| SCHEMBL2996960 | 0.72 | TRPA1 (0.44) | TRPA1ATMCYP1A2LMNAMEN1 | |
| SCHEMBL10320358 | 0.72 | TRPA1 (0.32) | TRPA1ATMTSHRACHEHTT | |
| SCHEMBL118540 | 0.69 | TSHR (0.40) | LMNACYP3A4HIF1ANAPRTTDP1 | |
| SCHEMBL29776884 | 0.69 | TRPA1 (0.44) | TRPA1ATMCYP1A2CYP3A4TSHR | |
| SCHEMBL9363776 | 0.69 | TRPA1 (0.44) | TRPA1ATMCYP1A2CYP3A4TSHR | |
| SCHEMBL9622609 | 0.67 | TSHR (0.38) | LMNACYP3A4HIF1ANAPRTTDP1 | |
| SCHEMBL4631055 | 0.67 | TSHR (0.38) | LMNACYP3A4HIF1ANAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406592-B | Reactive polysiloxanes and copolymers made therefrom | 莫门蒂夫性能材料股份有限公司 | 2020-09-22 | — | — | CN | disclosed |
| EP-3262103-B1 | REACTIVE POLYSILOXANES AND COPOLYMERS MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-11-28 | — | — | EP | disclosed |
| EP-3262103-A1 | REACTIVE POLYSILOXANES AND COPOLYMERS MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2018-01-03 | — | — | EP | disclosed |
| CN-107406592-A | Reactive polysiloxane and the copolymer being made from it | 莫门蒂夫性能材料股份有限公司 | 2017-11-28 | — | — | CN | disclosed |
| WO-2016137741-A1 | REACTIVE POLYSILOXANES AND COPOLYMERS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-09-01 | — | — | WO | disclosed |
| US-9334372-B1 | Reactive polysiloxanes and copolymers made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-05-10 | — | — | US | disclosed |