Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.77 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.77 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.77 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048961 | 0.91 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| Hydrochloric Acid SCHEMBL7611573 | 0.90 | CHRNB2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL21446827 | 0.89 | CHRNB2 (0.68) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL7611559 | 0.89 | CHRNB2 (0.68) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL1017796 | 0.87 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL7605815 | 0.87 | APOB (0.63) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL7607114 | 0.87 | CHRNB2 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL7611716 | 0.87 | CHRNB2 (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL7606412 | 0.87 | L3MBTL1 (0.64) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| Hydrochloric Acid SCHEMBL29598779 | 0.86 | CHRNB2 (0.96) | CHRNB2CHRNB4CHRNA3CHRNA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | CHRNB2 4877/4885CHRNB4 4881/4885CHRNA3 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.