Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558394 | 0.86 | CCR1 (0.42) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL1681797 | 0.86 | CCR1 (0.42) | KDM4ECCR1CCR5CCR8LMNA | |
| Dipyridyl SCHEMBL10945468 | 0.86 | KDM4E (0.48) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL29603676 | 0.79 | KDM4E (0.54) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL30485802 | 0.79 | LOXL2 (0.56) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL4535559 | 0.79 | KDM4E (0.54) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL7037544 | 0.79 | KDM4E (0.54) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL28416719 | 0.79 | KDM4E (0.54) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL7036361 | 0.79 | LOXL2 (0.56) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL4116786 | 0.79 | ASIC3 (0.53) | KDM4ENPC1SMN1; SMN2L3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580979-B1 | Method of detection by inducing electrochemiluminescence | IGEN INT INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0199804-B1 | LUMINESCENT METAL CHELATE LABELS AND MEANS FOR DETECTION | IGEN INC (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0580979-A2 | Luminescent metal chelate labels and means for detection | IGEN, INC. (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5238808-A | Biological substance attached to ruthenium or osmium complex | IGEN, INC. (US) | 1993-08-24 | — | — | US | disclosed |
| WO-1986002734-A1 | LUMINESCENT METAL CHELATE LABELS AND MEANS FOR DETECTION | HYPERION CATALYSIS INTERNATIONAL, INC. (US) | 1986-05-09 | — | — | WO | disclosed |