Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 4/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 4/20 | 1.00 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.70 |
| ▸ | SRC | P12931 | 2/20 | 0.70 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.70 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.70 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | FBP1 | P09467 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.70 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745804 | 1.00 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL27760096 | 0.90 | ADORA1 (0.82) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| Adenosine SCHEMBL11061671 | 0.85 | ADORA3 (0.85) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| Adenosine SCHEMBL11061662 | 0.85 | ADORA3 (0.85) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL6745798 | 0.85 | ADORA3 (1.00) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL10997946 | 0.85 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL7803298 | 0.85 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL12963362 | 0.85 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL5024895 | 0.85 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL481524 | 0.85 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515885-A | — | — | 2002-05-28 | — | — | JP | claimed |
| EP-0880353-A4 | COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION | THERASYS INC (US) | 2001-04-18 | — | — | EP | claimed |
| US-5998423-A | IN SKIN OR HAIR; ADMINISTERING ADENOSINE RECEPTOR ANTAGONIST | THERASYS, INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0880353-A1 | COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION | Therasys, Inc. (US) | 1998-12-02 | — | — | EP | claimed |
| WO-1998015276-A1 | COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION | THERASYS, INC. (US) | 1998-04-16 | — | — | WO | claimed |
| EP-0880353-A4 | COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION | THERASYS INC (US) | 2001-04-18 | — | — | EP | disclosed |
| US-5998423-A | IN SKIN OR HAIR; ADMINISTERING ADENOSINE RECEPTOR ANTAGONIST | THERASYS, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0880353-A1 | COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION | Therasys, Inc. (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998015276-A1 | COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION | THERASYS, INC. (US) | 1998-04-16 | — | — | WO | disclosed |