Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.36 |
| ▸ | ITGAL | P20701 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686537 | 0.88 | GPR84 (0.44) | ECE1GRIK1SLC1A2SLC1A1GRIK2 | |
| SCHEMBL5155261 | 0.85 | ECE1 (0.42) | ECE1ITGB2ICAM1ITGALTGFBR1 | |
| SCHEMBL7604126 | 0.84 | KMT2A (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL8601335 | 0.78 | ECE1 (0.47) | ECE1ITGB2ICAM1ITGALTGFBR1 | |
| SCHEMBL8634864 | 0.77 | CA2 (0.43) | ECE1CA2CA1GPR84 | |
| SCHEMBL10610009 | 0.77 | ECE1 (0.49) | ECE1ITGB2ICAM1ITGALTGFBR1 | |
| SCHEMBL5155757 | 0.77 | ECE1 (0.49) | ECE1ITGB2ICAM1ITGALTGFBR1 | |
| SCHEMBL29291292 | 0.76 | FOLH1 (0.47) | GPR84FFAR1 | |
| SCHEMBL23222804 | 0.76 | ECE1 (0.47) | ECE1ITGB2ICAM1ITGALTGFBR1 | |
| SCHEMBL20988053 | 0.76 | ECE1 (0.44) | ECE1ITGB2ICAM1ITGALTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088020-B1 | FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | USTAV MAKROMOLEKULARNI CHEMIE (CZ) | 2002-12-18 | — | — | EP | claimed |