Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5351575 | 0.95 | NPC1 (0.46) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL8920105 | 0.89 | ALDH1A1 (0.42) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27355090 | 0.88 | NPC1 (0.49) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL13437594 | 0.77 | PDK2 (0.50) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL12017104 | 0.77 | NPC1 (0.49) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL5353138 | 0.77 | HTR2A (0.64) | LMNASMN1; SMN2HTR2ATP53BCHE | |
| SCHEMBL7607194 | 0.75 | ALDH1A1 (0.46) | NPC1ALDH1A1LMNAMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL5352100 | 0.75 | ALDH1A1 (0.46) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL31026796 | 0.74 | TRPA1 (0.42) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL7609388 | 0.74 | HTR2A (0.42) | NPC1ALDH1A1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524624-B1 | Use of organometallic flurorenyl compounds. | PHILLIPS PETROLEUM CO (US) | 2002-05-15 | — | — | EP | claimed |
| EP-0666267-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-04-18 | — | — | EP | disclosed |