Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610512 | 0.87 | L3MBTL1 (0.61) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7611070 | 0.87 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG | |
| SCHEMBL7610932 | 0.85 | CHRNB2 (0.60) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7610893 | 0.83 | CHRNB2 (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG | |
| SCHEMBL7611172 | 0.82 | HTT (0.57) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7605010 | 0.81 | CHRNB2 (0.61) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7607213 | 0.81 | HTT (0.61) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7611690 | 0.81 | LMNA (0.56) | L3MBTL1PPARGAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7616965 | 0.80 | HDAC8 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG | |
| SCHEMBL7613182 | 0.79 | CHRNB2 (0.57) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | L3MBTL1 3333/4885CHRNB2 4877/4885CHRNB4 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.