SCHEMBL760609

SCHEMBL760609

CCCCCCCCC(CCCCCC)COC(=O)C(CC(=O)O)CC(CCCCCC)CCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 6/20 0.47
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
MMP2 P08253 6/20 0.41
MMP3 P08254 5/20 0.41
MMP1 P03956 3/20 0.41
MMP7 P09237 1/20 0.41
RECQL P46063 1/20 0.40
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PAM P19021 2/20 0.39
FFAR4 Q5NUL3 1/20 0.39
FFAR1 O14842 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7204185 0.86 CA2 (0.47) GPR84PRSS1PRSS2PRSS3RECQL
SCHEMBL566264 0.85 CYP3A4 (0.54) PRSS1PRSS2PRSS3RECQLCYP3A4
SCHEMBL9066913 0.82 GPR84 (0.55) GPR84MMP2MMP3MMP1MMP7
SCHEMBL5962565 0.82 GPR84 (0.55) GPR84MMP2MMP3MMP1MMP7
SCHEMBL27864192 0.82 GPR84 (0.55) GPR84MMP2MMP3MMP1MMP7
SCHEMBL4431314 0.82 GPR84 (0.55) GPR84MMP2MMP3MMP1MMP7
SCHEMBL19105124 0.82 PRSS1 (0.50) GPR84PRSS1PRSS2PRSS3RECQL
SCHEMBL6414894 0.82 PRSS1 (0.50) GPR84PRSS1PRSS2PRSS3RECQL
SCHEMBL20767414 0.82 PRSS1 (0.50) GPR84PRSS1PRSS2PRSS3RECQL
SCHEMBL28014163 0.81 GPR84 (0.54) GPR84PRSS1PRSS2PRSS3RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11090237-B2 Deodorant cosmetic compositions comprising calcium silicate and sodium bicarbonate HENKEL AG & CO. KGAA (DE) 2021-08-17 US disclosed
US-11045399-B2 Residue-minimized antiperspirant composition with improved skin feel HENKEL AG & CO. KGAA (DE) 2021-06-29 US disclosed
US-20200170901-A1 DEODORANT COSMETIC COMPOSITIONS COMPRISING CALCIUM SILICATE AND SODIUM BICARBONATE HENKEL AG & CO. KGAA (DE) 2020-06-04 US disclosed
US-20200170896-A1 ANHYDROUS DEODORANT COSMETIC COMPOSITIONS COMPRISING CALCIUM CARBONATE HENKEL AG & CO. KGAA (DE) 2020-06-04 US disclosed
US-20200129396-A1 STYLING PRODUCT FOR HEAD HAIR AND/OR BEARD HAIR II HENKEL AG & CO. KGAA (DE) 2020-04-30 US disclosed
US-20190183753-A1 RESIDUE-MINIMIZED ANTIPERSPIRANT COMPOSITION WITH IMPROVED SKIN FEEL HENKEL AG & CO. KGAA (DE) 2019-06-20 US disclosed
US-8574559-B2 Low-residue deodorant or antiperspirant stick based on an oil-in-water dispersion/emulsion HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2013-11-05 US disclosed
EP-1893301-B1 LOW-RESIDUE DEODORANT OR ANTIPERSPIRANT STICK BASED ON AN ETHANOL-CONTAINING OIL-IN-WATER DISPERSION/EMULSION HENKEL AG & CO KGAA (DE) 2012-03-21 EP disclosed
US-20100260698-A1 Anhydrous Antiperspirant Compositions with Improved Active Substance Release HENKEL AG & CO. KGAA (DE) 2010-10-14 US disclosed
US-20090010864-A1 Low residue deodorant or antiperspirant stick based on an ethanol-containing oil-in-water dispersion/emulsion HENKEL AG & CO. KGAA (DE) 2009-01-08 US disclosed
EP-1893301-A1 LOW-RESIDUE DEODORANT OR ANTIPERSPIRANT STICK BASED ON AN ETHANOL-CONTAINING OIL-IN-WATER DISPERSION/EMULSION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-03-05 EP disclosed
EP-1888179-A1 LOW-RESIDUE DEODORANT OR ANTIPERSPIRANT STICK BASED ON AN OIL-IN-WATER DISPERSION/EMULSION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-02-20 EP disclosed
WO-2006136330-A1 LOW-RESIDUE DEODORANT OR ANTIPERSPIRANT STICK BASED ON AN ETHANOL-CONTAINING OIL-IN-WATER DISPERSION/EMULSION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-28 WO disclosed
WO-2006119981-A1 LOW-RESIDUE DEODORANT OR ANTIPERSPIRANT STICK BASED ON AN OIL-IN-WATER DISPERSION/EMULSION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO disclosed
US-20020143072-A1 For use in pharmaceutical or cosmetic formulations COLLABORATIVE TECHNOLOGIES, INC. 2002-10-03 US disclosed
US-6379681-B1 CONTAINING NONIONIC SURFACTANT AND LECITHIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-30 US disclosed
US-6086787-A HEATING, THICKENING HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-11 US disclosed
US-5980874-A A SPRAYABLE, FINE-DROPLET, OIL-IN-WATER EMULSION COMPRISING WATER, NONIONIC EMULSIFIER, AN INORGANIC ASTRINGENT ANTIPERSPIRATION AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-11-09 US disclosed
US-5723137-A NONIONIC DISPERSANTS AND ESTERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-03-03 US disclosed
US-5494938-A COMPRISINGA WATER INSOLUABLE OIL, ALKYL GLUCOSIDES AND FATTY ACID GLYCERIDES; STORAGE STABILITY, HOMOGENEITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100260698-A1 Anhydrous Antiperspirant Compositions with Improved Active Substance Release CUTA, CYP2W1, IDUA GPR84 234/4885PRSS1 1393/4885PRSS2 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.