Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755985 | 0.86 | LTA4H (0.37) | KCNN4CYP3A4CYP2D6SIGMAR1MEN1 | |
| SCHEMBL15899496 | 0.84 | LMNA (0.40) | KCNN4LMNASCN1ASCN2ASCN3A | |
| SCHEMBL3972776 | 0.83 | SIGMAR1 (0.37) | MAPK1LMNACYP3A4SIGMAR1MEN1 | |
| SCHEMBL5962153 | 0.83 | KCNN4 (0.40) | KCNN4MAPK1LMNACYP3A4CYP2D6 | |
| SCHEMBL9187550 | 0.81 | KCNN4 (0.41) | KCNN4MAPK1LMNASCN1ASCN2A | |
| SCHEMBL479127 | 0.79 | KCNN4 (0.38) | KCNN4MAPK1LMNACYP3A4CYP2D6 | |
| SCHEMBL4058230 | 0.79 | TAAR1 (0.48) | KCNN4MAPK1KIF11TAAR1 | |
| SCHEMBL3891423 | 0.79 | KCNN4 (0.38) | KCNN4MAPK1LMNACYP3A4CYP2D6 | |
| SCHEMBL3663149 | 0.78 | CYP1A2 (0.45) | KCNN4LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL28893285 | 0.78 | MAPK1 (0.40) | KCNN4MAPK1LMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975570-B1 | PHENOKETALS AND THE USE THEREOF AS ODORIFEROUS SUBSTANCES | COGNIS DEUTSCHLAND GMBH (DE) | 2002-09-04 | — | — | EP | claimed |
| US-7560480-B2 | Alkyl-containing 5-acylindolinones, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| US-7560480-B2 | Alkyl-containing 5-acylindolinones, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| EP-0975570-B1 | PHENOKETALS AND THE USE THEREOF AS ODORIFEROUS SUBSTANCES | COGNIS DEUTSCHLAND GMBH (DE) | 2002-09-04 | — | — | EP | disclosed |
| US-6376457-B1 | 1-(1,1-DIETHOXYETHYL)-2,4-DIMETHYL BENZENE; DETERGENT, CLEANER, FABRIC SOFTENER, TEXTILE TREATMENT OR COSMETIC COMPOSITION. | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-04-23 | — | — | US | disclosed |
| EP-0975570-A1 | PHENOKETALS AND THE USE THEREOF AS ODORIFEROUS SUBSTANCES | Cognis Deutschland GmbH (DE) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045236-A1 | PHENOKETALS AND THE USE THEREOF AS ODORIFEROUS SUBSTANCES | COGNIS DEUTSCHLAND GMBH (DE) | 1998-10-15 | — | — | WO | disclosed |