Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618126 | 1.00 | L3MBTL1 (0.52) | L3MBTL1KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL21241652 | 0.84 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL22861532 | 0.84 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL21241611 | 0.82 | FKBP1A (0.49) | L3MBTL1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL22861528 | 0.82 | FKBP1A (0.49) | L3MBTL1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL7612086 | 0.81 | FKBP1A (0.46) | L3MBTL1KMT2AMAPK1POLBGAA | |
| SCHEMBL7421496 | 0.81 | FKBP1A (0.46) | L3MBTL1KMT2AMAPK1POLBGAA | |
| SCHEMBL11452675 | 0.80 | MAPK1 (0.44) | L3MBTL1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL22861533 | 0.80 | FKBP1A (0.53) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL21241612 | 0.80 | FKBP1A (0.53) | L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002522485-A | — | — | 2002-07-23 | — | — | JP | claimed |
| EP-1109554-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000009109-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| US-5843960-A | Inhibitors of rotamase enzyme activity | GPI NIL HOLDINGS, INC. (US) | 1998-12-01 | — | — | US | claimed |
| EP-1109554-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1011650-A1 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | Amgen Inc., (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-2000009109-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-1999014998-A2 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | AMGEN INC. (US) | 1999-04-01 | — | — | WO | disclosed |