Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861532 | 1.00 | L3MBTL1 (0.47) | L3MBTL1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22861528 | 0.88 | FKBP1A (0.49) | L3MBTL1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21241611 | 0.88 | FKBP1A (0.49) | L3MBTL1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21241612 | 0.86 | FKBP1A (0.53) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22861533 | 0.86 | FKBP1A (0.53) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7606506 | 0.84 | L3MBTL1 (0.52) | L3MBTL1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7618126 | 0.84 | L3MBTL1 (0.52) | L3MBTL1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21241653 | 0.82 | FKBP1A (0.52) | KDM4EALDH1A1 | |
| SCHEMBL22861597 | 0.82 | FKBP1A (0.52) | KDM4EALDH1A1 | |
| SCHEMBL8545744 | 0.79 | L3MBTL1 (0.48) | L3MBTL1KDM4EKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746440-B1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | UNIV TEXAS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2019152527-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-08 | — | — | WO | disclosed |