Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051013 | 0.86 | BCHE (0.60) | BCHEMEN1KMT2AANPEPTDP1 | |
| SCHEMBL6458060 | 0.86 | LMNA (0.64) | MEN1KMT2ATDP1SLC16A3LMNA | |
| SCHEMBL3698479 | 0.84 | BCHE (0.62) | BCHEOPRD1OPRK1DRD4MEN1 | |
| Hydrochloric Acid SCHEMBL6463866 | 0.84 | LMNA (0.67) | MEN1KMT2ATDP1SLC16A3LMNA | |
| SCHEMBL7608267 | 0.82 | MEN1 (0.68) | BCHEDRD4MEN1KMT2AMITF | |
| SCHEMBL13960329 | 0.82 | LMNA (0.72) | MEN1KMT2ATDP1SLC16A3LMNA | |
| SCHEMBL11288382 | 0.80 | SMN1; SMN2 (0.51) | BCHEMEN1KMT2ATDP1LMNA | |
| SCHEMBL7524412 | 0.80 | SMN1; SMN2 (0.51) | BCHEMEN1KMT2ATDP1LMNA | |
| SCHEMBL4427375 | 0.80 | DRD4 (0.59) | BCHEDRD4MEN1KMT2ATDP1 | |
| SCHEMBL9391272 | 0.80 | MEN1 (0.58) | BCHEDRD4MEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |