Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277988 | 0.90 | CA2 (0.61) | DRD4BCHEMEN1KMT2ATHRB | |
| SCHEMBL6540019 | 0.88 | NR1H2 (0.52) | DRD4BCHEPKMMEN1KMT2A | |
| SCHEMBL10054993 | 0.87 | MEN1 (0.74) | BCHEPKMMEN1KMT2ATDP1 | |
| SCHEMBL580289 | 0.86 | BCHE (0.77) | DRD4BCHEMEN1KMT2ATDP1 | |
| SCHEMBL3695539 | 0.86 | BCHE (0.77) | DRD4BCHEMEN1KMT2ATDP1 | |
| SCHEMBL6541651 | 0.85 | CA1 (0.63) | DRD4BCHEPKMHDAC8HDAC6 | |
| SCHEMBL1654 | 0.84 | MEN1 (0.78) | BCHEPKMMEN1KMT2ATDP1 | |
| Benzene SCHEMBL11697595 | 0.84 | MEN1 (0.78) | BCHEPKMMEN1KMT2ATDP1 | |
| SCHEMBL5799878 | 0.84 | MEN1 (0.78) | BCHEPKMMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9332806 | 0.84 | GAA (0.78) | DRD4BCHEMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938356-B1 | PROCESS FOR THE PRODUCTION OF A POLYBENZOXAZINE MONOMER | ARIANEGROUP SAS (FR) | 2024-09-18 | — | — | EP | disclosed |
| US-12065415-B2 | Process for the production of a polybenzoxazine monomer | ARIANEGROUP SAS (FR) | 2024-08-20 | — | — | US | disclosed |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20220177437-A1 | PROCESS FOR THE PRODUCTION OF A POLYBENZOXAZINE MONOMER | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE MONTPELLIER (FR) | 2022-06-09 | — | — | US | disclosed |
| EP-3938356-A1 | PROCESS FOR THE PRODUCTION OF A POLYBENZOXAZINE MONOMER | ArianeGroup SAS (FR) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020188182-A1 | PROCESS FOR THE PRODUCTION OF A POLYBENZOXAZINE MONOMER | ARIANEGROUP SAS (FR) | 2020-09-24 | — | — | WO | disclosed |
| CN-104961672-B | A kind of synthetic method of the tartrate of N (4 luorobenzyl) N (base of 1 methyl piperidine 4) N ' (4 isobutoxy benzyl) urea | 沈阳药科大学 | 2017-10-20 | — | — | CN | disclosed |
| EP-2822941-B1 | BENZODIOXANES IN COMBINATION WITH STATINS FOR INHIBITING LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2017-05-10 | — | — | EP | disclosed |
| CN-104961672-A | Synthetic method of tartrate of N-(4-fluorobenzyl)-N-(1-methylpiperidine-4-yl)-N'-(4-isobutoxybenzyl)urea | UNIV SHENYANG PHARMACEUTICAL | 2015-10-07 | — | — | CN | disclosed |
| EP-2336125-A1 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | Janssen Pharmaceutica N.V. (BE) | 2011-06-22 | — | — | EP | disclosed |
| EP-1384720-A1 | Process for drying paroxetine hydrochloride | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-1384711-A1 | Optical resolution of a piperidine derivative | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-6610851-B1 | 1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-((3,4-methylene dioxyphenyl)oxymethyl)piperidine; reacting 4-(4-fluorophenyl)-3-hydroxymethylpiperidine with di-tert-butyl dicarbonate to form the carbamate; 3,4-methylenedioxyphenol | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-08-26 | — | — | US | disclosed |
| US-20030144519-A1 | Process for preparing a piperidine derivative | SUMIKA FINE CHEMICALS CO., LTD. | 2003-07-31 | — | — | US | disclosed |
| US-6476227-B1 | Piperidine derivative and process for preparing the same | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1124802-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | Synthon B.V. (NL) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026187-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | SYNTHON B.V. (NL) | 2000-05-11 | — | — | WO | disclosed |
| US-5948914-A | PREPARING 4-(4-FLUOROPHENYL)-3-HYDROXYMETHYLPIPERIDINE BY OPTICALLY RESOLVING WITH O-CHLOROTARTRANILIC ACID; CHEMICAL INTERMEDIATE FOR DRUGS | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0812827-A1 | Piperidine derivative as intermediates for the preparation of paroxetine and process for their preparation | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177437-A1 | PROCESS FOR THE PRODUCTION OF A POLYBENZOXAZINE MONOMER | WIZ, PCBP1, TERB1 | DRD4 2080/4885BCHE 2256/4885PKM 1320/4885 |
| US-12065415-B2 | Process for the production of a polybenzoxazine monomer | WIZ, PCBP1, TERB1 | DRD4 2080/4885BCHE 2256/4885PKM 1320/4885 |
| US-20030144519-A1 | Process for preparing a piperidine derivative | TPH1, TPH2, HTR7 | DRD4 8/4885BCHE 1046/4885PKM 303/4885 |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | DRD4 4866/4885BCHE 2641/4885PKM 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.