Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6463866 | 0.98 | LMNA (0.67) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL13960329 | 0.95 | LMNA (0.72) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL10877713 | 0.91 | LMNA (0.60) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL7278068 | 0.89 | LMNA (0.77) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL2289990 | 0.89 | LMNA (0.77) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL1849603 | 0.89 | LMNA (0.77) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL10133058 | 0.86 | LMNA (0.84) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL7606905 | 0.86 | BCHE (0.53) | LMNASLC16A3MEN1KMT2ATDP1 | |
| SCHEMBL2295189 | 0.85 | LMNA (0.62) | LMNASLC16A3KDM4EL3MBTL1MEN1 | |
| SCHEMBL14646432 | 0.85 | LMNA (0.68) | LMNASLC16A3KDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005108381-A1 | SYNTHESIS AND USES OF SYNEPHRINE DERIVATIVES | SYNTECH (SSPF) INTERNATIONAL INC. (US) | 2005-11-17 | — | — | WO | disclosed |
| US-20050250944-A1 | Synthesis and uses of synephrine derivatives | SYNTECH (SSPF) INTERNATIONAL INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250944-A1 | Synthesis and uses of synephrine derivatives | ADRB3, ADRB2, ADRB1 | LMNA 642/4885SLC16A3 3620/4885KDM4E 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.