Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254921 | 0.78 | NPSR1 (0.50) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL4725978 | 0.73 | MAPK1 (0.66) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL1036342 | 0.73 | MAPK1 (0.66) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL7606395 | 0.72 | MAPT (0.52) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL7255199 | 0.71 | NPSR1 (0.49) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL7608097 | 0.70 | KDM4E (0.51) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL7607397 | 0.70 | KDM4E (0.51) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL7254995 | 0.70 | MAPT (0.45) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL27756710 | 0.70 | CPA1 (0.49) | NPSR1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL7256110 | 0.69 | NPSR1 (0.47) | NPSR1KDM4EMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | AMERICAN CYANAMID COMPANY | 2002-08-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | SULT1E1, SULT1A1, TST | NPSR1 151/4885KDM4E 3215/4885MAPT 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.