Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 8/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608097 | 1.00 | KDM4E (0.51) | KDM4EMAPTMAPK1NPSR1APOBEC3G | |
| SCHEMBL7606395 | 0.79 | MAPT (0.52) | KDM4EMAPTMAPK1NPSR1APOBEC3G | |
| SCHEMBL7254921 | 0.77 | NPSR1 (0.50) | KDM4EMAPTMAPK1NPSR1APOBEC3G | |
| SCHEMBL7606406 | 0.76 | MAPT (0.47) | KDM4EMAPTMAPK1NPSR1APOBEC3G | |
| SCHEMBL8064895 | 0.75 | GRM8 (0.49) | MAPTNPSR1 | |
| SCHEMBL1913648 | 0.75 | KIF11 (0.50) | KIF11GRM2GRM3ALPIPKM | |
| SCHEMBL7317301 | 0.75 | KIF11 (0.50) | KIF11GRM2GRM3ALPIPKM | |
| SCHEMBL4725978 | 0.74 | MAPK1 (0.66) | KDM4EMAPTMAPK1NPSR1APOBEC3G | |
| SCHEMBL1036342 | 0.74 | MAPK1 (0.66) | KDM4EMAPTMAPK1NPSR1APOBEC3G | |
| SCHEMBL10869934 | 0.74 | NPSR1 (0.48) | KDM4EMAPTMAPK1NPSR1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | AMERICAN CYANAMID COMPANY | 2002-08-01 | — | — | US | claimed |
| US-6358883-B1 | FOR CONTROLLING NEMATODE, INSECT AND ACARID PESTS | AMERICAN CYANAMID COMPANY | 2002-03-19 | — | — | US | claimed |
| EP-1000934-A2 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | American Cyanamid Company (US) | 2000-05-17 | — | — | EP | claimed |
| US-6482962-B2 | CONTACTING HELMINTH, NEMATODE, INSECT OR ACARID PESTS OR PARASITES OR THEIR FOOD SUPPLY, HABITAT OR BREEDING GROUNDS WITH A NITROETHYL DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | disclosed |
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | AMERICAN CYANAMID COMPANY | 2002-08-01 | — | — | US | disclosed |
| US-6358883-B1 | FOR CONTROLLING NEMATODE, INSECT AND ACARID PESTS | AMERICAN CYANAMID COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1000934-A2 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | American Cyanamid Company (US) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | SULT1E1, SULT1A1, TST | KDM4E 3215/4885MAPT 4666/4885MAPK1 2754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.