SCHEMBL7607702

SCHEMBL7607702

CC(C)(C)c1cc(Cn2c(=O)[nH]c(=O)n(Cc3ccc(O)c(C(C)(C)C)c3)c2=O)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
THRA P10827 1/20 0.42
ALDH1A1 P00352 6/20 0.41
HTT P42858 3/20 0.41
ALOX15 P16050 2/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 2/20 0.41
NR1I2 O75469 1/20 0.41
CYP2C9 P11712 1/20 0.41
MIF P14174 1/20 0.41
TYR P14679 1/20 0.41
NFE2L2 Q16236 1/20 0.41
MAPT P10636 4/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
KDM4E B2RXH2 3/20 0.39
HSP90AA1 P07900 4/20 0.38
HSP90AB1 P08238 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5155008 0.91 ALDH1A1 (0.48) THRBTHRAALDH1A1HTTALOX15
SCHEMBL7601523 0.89 THRB (0.42) THRBTHRAALDH1A1HTTALOX15
SCHEMBL698535 0.84 ALDH1A1 (0.49) THRBALDH1A1HTTALOX15LMNA
SCHEMBL7607371 0.81 ESR1 (0.49) THRBALDH1A1HTTLMNAMAPT
SCHEMBL7605117 0.78 ERCC1 (0.36) THRBTHRAALDH1A1HTTALOX15
SCHEMBL5472793 0.77 GAA (0.47) THRBTHRAALDH1A1HTTLMNA
SCHEMBL31375 0.73 ALDH1A1 (0.57) THRBALDH1A1HTTALOX15LMNA
SCHEMBL456005 0.72 ALDH1A1 (0.49) THRBALDH1A1HTTALOX15LMNA
SCHEMBL2919862 0.70 ALDH1A1 (0.59) ALDH1A1HTTALOX15LMNAHSD17B10
SCHEMBL7199857 0.70 ALDH1A1 (0.59) ALDH1A1HTTALOX15LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115644556-A Cushioning element utilizing foam particles 耐克创新有限合伙公司 2023-01-31 CN disclosed
CN-115644557-A Cushioning element utilizing foam particles 耐克创新有限合伙公司 2023-01-31 CN disclosed
US-6451888-B1 Solid stabilizer composition with improved hydrolytic stability GENERAL ELECTRIC COMPANY 2002-09-17 US disclosed
US-6033600-A PENTAERYTHRITOL PHOSPHITE, A HINDERED PHENOLIC ISOCYANURATE, A METAL SALT OF A FATTY ACID AND HYDROTALCITE. GENERAL ELECTRIC COMPANY (US) 2000-03-07 US disclosed
EP-0685516-B1 Solid stabilizer composition with improved hydrolytic stability GEN ELECTRIC (US) 1999-08-04 EP disclosed
EP-0685516-A1 Solid stabilizer composition with improved hydrolytic stability GENERAL ELECTRIC COMPANY (US) 1995-12-06 EP disclosed
US-5162406-A Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol THE DOW CHEMICAL COMPANY (US) 1992-11-10 US disclosed
US-4923909-A THIXOTROPIC SLURRYING; PIPES; STABILITY; THERMOPLASTIC OR THERMOSETTING RESIN; LIQUID CARRIER THE B. F. GOODRICH COMPANY (US) 1990-05-08 US disclosed
US-4025486-A PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1977-05-24 US disclosed