SCHEMBL456005

SCHEMBL456005

CC(C)(C)c1cc(Cn2c(=O)[nH]c(=O)[nH]c2=O)cc(C(C)(C)C)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.49
KDM4E B2RXH2 5/20 0.49
MAPT P10636 5/20 0.49
TDP1 Q9NUW8 2/20 0.49
GAA P10253 6/20 0.46
TSHR P16473 5/20 0.46
LMNA P02545 3/20 0.46
HPGD P15428 2/20 0.46
POLB P06746 1/20 0.46
THRB P10828 1/20 0.46
MAPK1 P28482 3/20 0.44
MEN1 O00255 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BLM P54132 2/20 0.44
KMT2A Q03164 2/20 0.44
ATM Q13315 2/20 0.44
HIF1A Q16665 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14472121 0.89 TDP1 (0.46) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL698535 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL8914968 0.87 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL28529861 0.85 GAA (0.44) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL8755484 0.85 GAA (0.39) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL7601523 0.84 THRB (0.42) ALDH1A1KDM4EMAPTTDP1LMNA
SCHEMBL31375 0.83 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL21694100 0.82 GAA (0.44) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL29013803 0.79 ALDH1A1 (0.44) ALDH1A1KDM4EMAPTTDP1GAA
SCHEMBL7631700 0.79 MAOA (0.40) ALDH1A1KDM4EMAPTTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115785522-B Azeotroping agent generating system and thermoplastic vulcanized rubber 道恩高材(北京)科技有限公司 2024-06-25 CN claimed
CN-118222220-A Photovoltaic packaging material and preparation method thereof 浙江利昌科技有限公司 2024-06-21 CN claimed
CN-115210311-B Dust free blends 瑞士新集团股份有限公司 2024-06-18 CN claimed
US-20240174839-A1 STABILIZER MIXTURE BASF SE (DE) 2024-05-30 US claimed
CN-118063895-A Extrusion-blowing transparent polypropylene resin and preparation method thereof 中国神华煤制油化工有限公司 2024-05-24 CN claimed
CN-118063780-A Polyester catalyst, and preparation method and application thereof 中国石油化工股份有限公司 2024-05-24 CN claimed
CN-117601541-B Colorful multilayer electroplating TPU film and preparation method and application thereof 东莞市全丰新材料科技有限公司 2024-05-24 CN claimed
CN-118027558-A Polypropylene compound and preparation method and application thereof 金发科技股份有限公司 2024-05-14 CN claimed
CN-117777939-B UV (ultraviolet) acrylic glue, preparation method thereof and optical film 苏州弘德光电材料科技有限公司 2024-05-14 CN claimed
CN-118027847-A Application of compound as ultraviolet light conversion agent 江苏绿人半导体有限公司 2024-05-14 CN claimed
US-20030005621-A1 Candle wax stabilized with morpholinones CIBA SPECIALTY CHEMICALS CORP. 2003-01-09 US claimed
EP-0894275-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE TRANSITIONS OPTICAL INC (US) 2000-03-29 EP claimed
EP-0680486-B1 HYDROLYTICALLY STABLE PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORP (US) 1999-03-24 EP claimed
EP-0894275-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE TRANSITIONS OPTICAL, INC. (US) 1999-02-03 EP claimed
US-5703006-A LIGHTFASTNESS, HEAT RESISTANCE RICOH COMPANY, LTD. (JP) 1997-12-30 US claimed
WO-1997040409-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE TRANSITIONS OPTICAL, INC. (US) 1997-10-30 WO claimed
US-5141995-A Melting, kneading and Blending with polyol fatty acid, phenolic antioxidant, radical generating agent CHISSO CORPORATION (JP) 1992-08-25 US claimed
EP-0110293-A2 Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof The B.F. GOODRICH Company (US) 1984-06-13 EP claimed
EP-0106169-A1 Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof The B.F. GOODRICH Company (US) 1984-04-25 EP claimed
US-4415686-A Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof THE B. F. GOODRICH COMPANY (US) 1983-11-15 US claimed