Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27958966 | 0.79 | LMNA (0.46) | ALDH1A1SMN1; SMN2PKMIDO1APP | |
| SCHEMBL425010 | 0.78 | LMNA (0.48) | ALDH1A1SMN1; SMN2PKMIDO1APP | |
| SCHEMBL7283077 | 0.78 | CALM1 (0.55) | MAOBALDH1A1GAAIDO1L3MBTL1 | |
| SCHEMBL13067926 | 0.78 | IDO1 (0.47) | ALDH1A1GAASMN1; SMN2PKMIDO1 | |
| SCHEMBL531291 | 0.78 | SMN1; SMN2 (0.47) | MAOBMAOAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL530937 | 0.78 | IDO1 (0.47) | ALDH1A1GAASMN1; SMN2PKMIDO1 | |
| SCHEMBL25316972 | 0.77 | IDO1 (0.46) | MAOBMAOAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL25919391 | 0.77 | IDO1 (0.46) | MAOBMAOAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8881221 | 0.76 | CALM1 (0.56) | MAOBALDH1A1GAASMN1; SMN2IDO1 | |
| SCHEMBL62037 | 0.75 | IDO1 (0.59) | MAOBMAOAALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212096-A2 | DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME | Brenner, Sydney (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001013958-A2 | DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME | BRENNER SYDNEY (US) | 2001-03-01 | — | — | WO | disclosed |