Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607722 | 0.83 | CYP19A1 (0.37) | CYP19A1APPNPC1HPGDRAB9A | |
| SCHEMBL5206971 | 0.78 | CYP19A1 (0.47) | CYP19A1FFAR4SMN1; SMN2 | |
| SCHEMBL7606241 | 0.78 | CYP19A1 (0.41) | CYP19A1FOLH1APPFFAR4 | |
| SCHEMBL5203737 | 0.75 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL7606232 | 0.75 | CYP19A1 (0.41) | CYP19A1FOLH1APP | |
| SCHEMBL6139688 | 0.74 | CYP19A1 (0.45) | CYP19A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL6139684 | 0.73 | CYP19A1 (0.48) | CYP19A1SMN1; SMN2 | |
| SCHEMBL7611458 | 0.71 | APP (0.42) | CYP19A1APPFFAR4NPC1RAB9A | |
| SCHEMBL7611451 | 0.71 | APP (0.42) | CYP19A1APPFFAR4NPC1RAB9A | |
| SCHEMBL4290486 | 0.70 | PTPN1 (0.45) | CYP19A1FOLH1KMT2AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |