Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292376 | 0.83 | CYP19A1 (0.48) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL964882 | 0.83 | L3MBTL1 (0.44) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL964883 | 0.83 | L3MBTL1 (0.44) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL7536141 | 0.81 | L3MBTL1 (0.44) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL7532766 | 0.81 | L3MBTL1 (0.44) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL963777 | 0.80 | MEN1 (0.52) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL964676 | 0.79 | NPC1 (0.46) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL7618225 | 0.78 | L3MBTL1 (0.40) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL3286888 | 0.78 | ALDH1A1 (0.48) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 | |
| SCHEMBL7528094 | 0.77 | NPC1 (0.46) | PTPN1PTPN2PTPN6CYP19A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035004-A1 | PHENYL SUBSTITUTED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS POSSESSING BETA AGONIST ACTIVITY | Parion Sciences, Inc. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146869-A1 | PHENYL SUBSTITUTED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS POSSESSING BETA AGONIST ACTIVITY | PARION SCIENCES, INC. (US) | 2007-12-21 | — | — | WO | disclosed |