Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.33 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606232 | 0.84 | CYP19A1 (0.41) | CYP19A1CA1CA2ACHEAPP | |
| SCHEMBL7607726 | 0.83 | CYP19A1 (0.38) | CYP19A1APPNPC1HPGDRAB9A | |
| SCHEMBL7606241 | 0.81 | CYP19A1 (0.41) | CYP19A1CA1CA2ACHEAPP | |
| SCHEMBL7605348 | 0.78 | CYP19A1 (0.44) | CYP19A1F2F10PRSS1F7 | |
| SCHEMBL7605339 | 0.78 | CYP19A1 (0.44) | CYP19A1F2F10PRSS1F7 | |
| SCHEMBL5206971 | 0.77 | CYP19A1 (0.47) | CYP19A1ALDH1A1F2SMN1; SMN2 | |
| SCHEMBL7530567 | 0.75 | L3MBTL1 (0.38) | CYP19A1ALDH1A1 | |
| SCHEMBL7530324 | 0.75 | L3MBTL1 (0.38) | CYP19A1ALDH1A1 | |
| SCHEMBL14090693 | 0.75 | CYP19A1 (0.39) | CYP19A1ACP1PTPN12PTPN13SSU72 | |
| SCHEMBL5203737 | 0.75 | CYP19A1 (0.47) | CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |