Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332333 | 0.86 | MTNR1A (0.65) | MTNR1AMTNR1BIDO1CYP2A6SMN1; SMN2 | |
| SCHEMBL14521480 | 0.85 | IDO1 (0.61) | MTNR1AMTNR1BIDO1CYP2C19KMT2A | |
| SCHEMBL14615462 | 0.83 | IDO1 (0.59) | MTNR1AMTNR1BIDO1CYP2A6SMN1; SMN2 | |
| SCHEMBL8132742 | 0.83 | MTNR1A (0.67) | MTNR1AMTNR1BIDO1 | |
| SCHEMBL14615472 | 0.82 | IDO1 (0.57) | MTNR1AMTNR1BIDO1CYP2A6SMN1; SMN2 | |
| SCHEMBL5347056 | 0.81 | MTNR1A (0.74) | MTNR1AMTNR1BIDO1CYP1A2BLM | |
| SCHEMBL14615597 | 0.81 | IDO1 (0.56) | MTNR1AMTNR1BIDO1CYP2A6SMN1; SMN2 | |
| SCHEMBL27709630 | 0.81 | IDO1 (0.56) | MTNR1AMTNR1BIDO1CYP2A6SMN1; SMN2 | |
| SCHEMBL8130906 | 0.81 | MTNR1A (0.65) | MTNR1AMTNR1BIDO1MEN1CYP1A2 | |
| SCHEMBL6076645 | 0.80 | MTNR1A (0.72) | MTNR1AMTNR1BCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | claimed |
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| US-5616575-A | COCAINE ADDICTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1997-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | CCNB1, CCNB2, CCNA1 | MTNR1A 586/4885MTNR1B 498/4885IDO1 1432/4885 |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | MTNR1A 194/4885MTNR1B 337/4885IDO1 166/4885 |
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | MTNR1A 478/4885MTNR1B 262/4885IDO1 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.