Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | BCL2 | P10415 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610278 | 0.86 | L3MBTL1 (0.55) | L3MBTL1BCHEPTGS1PTGS2LMNA | |
| SCHEMBL6320470 | 0.84 | CALM1 (0.47) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6326374 | 0.80 | SMN1; SMN2 (0.46) | BCL2MAPTMAOAMAOBSMN1; SMN2 | |
| SCHEMBL6320217 | 0.80 | SMN1; SMN2 (0.46) | BCL2SMN1; SMN2 | |
| SCHEMBL11627146 | 0.80 | BCL2 (0.50) | L3MBTL1BCHEBCL2PTGS1PTGS2 | |
| SCHEMBL11621170 | 0.78 | CYP1A2 (0.53) | L3MBTL1BCHEBCL2PTGS1PTGS2 | |
| SCHEMBL11840883 | 0.77 | L3MBTL1 (0.57) | L3MBTL1BCHEPTGS1PTGS2LMNA | |
| SCHEMBL10787566 | 0.75 | PTGS1 (0.56) | L3MBTL1BCHEBCL2PTGS1PTGS2 | |
| SCHEMBL11626181 | 0.74 | BCHE (0.59) | BCHEGAA | |
| SCHEMBL11125959 | 0.72 | SMN1; SMN2 (0.57) | BCL2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |