Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18675838 | 0.87 | ALDH1A1 (0.40) | ALOX15CPB2KMT2ABLMPMP22 | |
| SCHEMBL14464925 | 0.83 | ALOX15 (0.41) | ALOX15CPB2KMT2ABLMPMP22 | |
| SCHEMBL12150082 | 0.75 | TDP1 (0.44) | KMT2AL3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL6671591 | 0.75 | ALDH1A1 (0.39) | KMT2AALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL3314941 | 0.75 | ALOX15 (0.44) | ALOX15CPB2KMT2ABLMPMP22 | |
| SCHEMBL1538912 | 0.75 | ALOX15 (0.54) | ALOX15CPB2KMT2ABLMPMP22 | |
| SCHEMBL1538915 | 0.75 | ALOX15 (0.54) | ALOX15CPB2KMT2ABLMPMP22 | |
| SCHEMBL25141834 | 0.73 | ALOX15 (0.43) | ALOX15CPB2KMT2ABLMPMP22 | |
| Hydrochloric Acid SCHEMBL1487697 | 0.73 | ALOX15 (0.52) | ALOX15CPB2KMT2ABLMPMP22 | |
| Hydrochloric Acid SCHEMBL1487698 | 0.73 | ALOX15 (0.52) | ALOX15CPB2KMT2ABLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5411967-A | Antiinflammatory, immunosuppressant, antitumor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |