Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608496 | 0.87 | ALOX15 (0.45) | ALDH1A1LMNAHSD17B10ALOX15CPB2 | |
| SCHEMBL1268708 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10ALOX15CPB2 | |
| SCHEMBL14464925 | 0.81 | ALOX15 (0.41) | ALDH1A1LMNAHSD17B10ALOX15CPB2 | |
| SCHEMBL7399674 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15CPB2 | |
| SCHEMBL7399669 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15CPB2 | |
| SCHEMBL15322887 | 0.77 | FOLH1 (0.33) | TSHRTDP1 | |
| SCHEMBL6685614 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| SCHEMBL10643598 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15GLO1 | |
| SCHEMBL12150082 | 0.74 | TDP1 (0.44) | ALDH1A1LMNAHSD17B10KMT2AHPGD | |
| SCHEMBL9439802 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10ALOX15GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088576-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088576-A1 | ANTIVIRAL COMPOUNDS | EIF2AK2, MAVS, ITPA | ALDH1A1 4716/4885LMNA 2219/4885HSD17B10 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.