Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608511 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KEAP1FFAR1GRIN1GRIN2B | |
| SCHEMBL7280063 | 0.87 | KEAP1 (0.54) | ALDH1A1KEAP1FFAR1GRIN1GRIN2B | |
| SCHEMBL11435918 | 0.82 | KEAP1 (0.48) | ALDH1A1KEAP1FFAR1GRIN1GRIN2B | |
| SCHEMBL10749652 | 0.80 | GRIN1 (0.47) | ALDH1A1KEAP1FFAR1GRIN1GRIN2B | |
| SCHEMBL10749659 | 0.80 | GRIN1 (0.47) | ALDH1A1KEAP1FFAR1GRIN1GRIN2B | |
| SCHEMBL5604545 | 0.79 | CTBP2 (0.48) | ALDH1A1KDM4EKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL5604550 | 0.79 | CTBP2 (0.48) | ALDH1A1KDM4EKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL14423596 | 0.77 | KEAP1 (0.64) | ALDH1A1KEAP1FFAR1TDP1HDAC2 | |
| SCHEMBL5348465 | 0.77 | KEAP1 (0.64) | ALDH1A1KEAP1FFAR1TDP1HDAC2 | |
| SCHEMBL5348463 | 0.77 | KEAP1 (0.64) | ALDH1A1KEAP1FFAR1TDP1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403794-B2 | REACTING A BIGUANIDINE WITH AN ALKOXYCARBONYL, OR A SUBSTITUTED TRIAZINE WITH AMMONIA OR AN ALKYLAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| US-6346503-B1 | PRE- AND POSTEMERGENCE HERBICIDES FOR CROPS LIKE CORN, WHEAT, AND COTTON | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-12 | — | — | US | disclosed |
| US-20020016459-A1 | Substituted 2-amino-4-alkylamino-1,3,5-triazines as herbicides | RIEBEL HANS-JOCHEM (DE) | 2002-02-07 | — | — | US | disclosed |
| EP-0934284-A1 | SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AG (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015537-A1 | SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016459-A1 | Substituted 2-amino-4-alkylamino-1,3,5-triazines as herbicides | AHR, DDT, CYP1A1 | ALDH1A1 129/4885KEAP1 314/4885FFAR1 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.